DOI: 10.33917/es-1.187.2023.78-85

Nanocorpuscular mutagenesis is the property of nanoparticles and/or nanomaterials to induce genetic changes or mutations.

Research on this newly discovered phenomenon will certainly expand the sphere of activity of geneticists and biologists, since scientists will have new tools at their disposal. Ideally, these studies will create a fundamentally new experimental basis for deeper understanding of the development processes in a living matter, and will complement our knowledge of what can and cannot be done with nature. In theoretical terms, it can also be admitted that the means of nanocorpuscular mutagenesis would pave a new way to obtaining and understanding such genetic and biological forms that favourably differ from those, which served as the basis for natural selection on our planet for hundreds of millions of years. From a practical point of view, one might expect that methodology of nanocorpuscular mutagenesis in combination with other progressive research methods will open up new interesting prospects in the field of genetic technologies, aimed, as is known, at solving such global, vital problems as:

– induction of hereditary immunity;

– fight against viral and oncological diseases;

– creation of new unique varieties of cultivated plants and animal breeds with such features that will be extremely useful and valuable for agricultural economy.

In other words, nanocorpuscular mutagenesis is likely to become another means of deep reformation of the fundamental apparatus of heredity and, as a result, transformation of the living systems’ ontology and will also make a valuable contribution to genetic science by discovering new, hitherto unknown phenomena and patterns.

References:

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2. Zakhidov S.T. Vystuplenie na zasedanii Prezidiuma RAN 13 oktyabrya 2013 g. v ramkakh obsuzhdeniya nauchnogo soobshcheniya Yu.M. Evdokimova “Strukturnaya nanotekhnologiya nukleinovykh kislot: sozdanie ‘zhidkikh’ i ‘tverdykh’ nanokonstruktsii DNK”: Stenograficheskii otchet [Speech at the meeting of the Presidium of the Russian Academy of Sciences on October 13, 2013 as part of discussion of the scientific report by Y.M. Evdokimov “Structural Nanotechnology of Nucleic Acids: Creation of ‘Liquid’ and ‘Solid’ DNA Nanostructures”: Verbatim Report]. Vestnik Rossiiskoi akademii nauk, 2014, vol 84, pp. 20–33.

3. Zakhidov S.T. O nanotekhnologiyakh v sisteme nauk [About Nanotechnologies in the System of Sciences]. Vestnik R ossiiskoi akademii nauk, 2021, vol. 91, no 3, pp. 289–292.

4. Rapoport I.A. Khimicheskii mutagenez: teoriya i praktika [Chemical Mutagenesis: Theory and Practice]. Moscow, Znanie (repr. izd.), 2013, 86 p.

5. Kohl Y., Runden-Pran E., Mariussen E., et al. Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment: A Review. Nanomaterials, 2020, vol. 10, no 10.

DOI: https://doi.org/10.33917/es-4.184.2022.113-119

“Viruses stand on the borders of the living and non-living. On the one hand, they have all the attributes of a living thing: they are born, assimilate, die and, to please those who are accustomed to seeing movement in the living, move. But in chemical laboratories viruses are sometimes transformed into powder, which in appearance doesn’t differ much from a mineral that has been ground into powder. And this “viral” powder is not born, does not assimilate, does not die and, of course, if it moves, then only for the same reasons as granulated sugar. But once the virus powder, sleeping in a “dead sleep” for a long time, longer than the “sleeping princess”, is “transferred” into a living environment, for example, tobacco mosaic virus is put onto tobacco leaves, the powder in the plant cells will turn into tailed living beings. If a virus is alive, why doesn’t it die when it turns into a corpse? If it is lifeless, why, having resurrected, it lives like all living things?” (N.K. Koltsov)

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